Siramesine Catalog No.:M10504-10 Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10

Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10

Smiles: COC1=CC=C(CCC(=O)NC2=NC3=CC=C(Cl)C=C3S2)C=C1OC

CAS Number: 486424-20-8

AZ5104 display minimal off-target activity against other non-HER family kinases

CAS Number: 343787-29-1

Siramesine Catalog No.:M10504-10 Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10Siramesine, also known as Lu 28 179, is a potent sigma 2 receptor agonist. Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes. Siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation. Siramesine involves lysosomal leakage and oxidative stress. Product information CAS Number: 147817 50 3 Molecular Weight: 454. 58 Formula: C30H31FN2O Chemical Name: 1' {4 [1 (4 fluorophenyl)