Lenvatinib - CAS# 417716-92-8 Catalog No.:M8564-10 2-amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-

2-amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-

and selective VHL based dual degrader probe of BRD9 and BRD7 with DC50s of 4

1898283-02-7

H3255 (L858R) and H1650 (ex19del)

BG45 was used at 10 µM final concentration in various in vitro assays

Lenvatinib - CAS# 417716-92-8 Catalog No.:M8564-10 2-amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-Lenvatinib, also known as E7080, is a synthetic, orally available inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR FLK 1) tyrosine kinase with potential antineoplastic activity. E7080 blocks VEGFR2 activation by VEGF, resulting in inhibition of the VEGF receptor signal transduction pathway, decreased vascular endothelial cell migration and proliferation, and vascular endothelial cell apoptosis. Product information