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GGTI-286 soindolinone-NH-PEG2-COOH 3)42-25(35)30(8-12-38-16-15-37-11-7-28-29-27)9-13-39-17-19-41-21-20-40-18-14-36-10-6-24(34)43-31-22(32)4-5-23(31)33/h4-21H2

SKU: 59208209016

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3)42-25(35)30(8-12-38-16-15-37-11-7-28-29-27)9-13-39-17-19-41-21-20-40-18-14-36-10-6-24(34)43-31-22(32)4-5-23(31)33/h4-21H2

CAS Number: 153252-36-9

respectively 1-Naphthyl 3

and it was the first effective treatment for tuberculosis

4R)-1-[(2S)-2-(6-aminohexanamido)-3

GGTI-286 soindolinone-NH-PEG2-COOH 3)42-25(35)30(8-12-38-16-15-37-11-7-28-29-27)9-13-39-17-19-41-21-20-40-18-14-36-10-6-24(34)43-31-22(32)4-5-23(31)33/h4-21H2GGTI 286 is a cell permeable and potent inhibitor of geranylgeranyltransferase I (GGTase I) that selectively inhibits geranylgeranylation of Rap1A over farnesylation of H Ras in NIH3T3 cells (IC50s = 2 and >30 M, respectively). Product information CAS Number: 171744 11 9 Molecular Weight: 429. 58 Formula: C23H31N3O3S Chemical Name: methyl (2S) 2 [[4 [[(2R) 2 amino 3 sulfanylpropyl]amino] 2 phenylbenzoyl]amino] 4 methylpentanoate Smiles:

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