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Smiles: NC1=CC=CN=C1/C=N/NC(N)=S
It inhibits EGFR and induces upregulation of acetylated histone H3 in a dosedependent fashion
16(2):205-13
Kadereit D
BG45 was used at 10 µM final concentration in various in vitro assays
KB-R7943 - CAS# 182004-65-5 60131 Smiles: NC1=CC=CN=C1/C=N/NC(N)=SKB R7943, CAS No. 182004 65 5, is a potent, selective inhibitor of the reverse mode of the Na+ Ca2+ exchanger (IC50 = 0. 7 M). KB R7943 does not modify secondary pathology in the thalamus following focal cerebral stroke in rats. KB R7943 blocks opening of the mitochondrial permeability transition pore. KB R7943 restores endothelium dependent relaxation induced by advanced glycosylation end products in rat aorta. KB R7943 inhibits high glucose induced