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72 hours) shows no detectable cells in G1 and G2 in promyelocytic leukemia cells and arrest of cells in G1 in synchronized human non-small cell lung carcinoma (H-460) and human normal lung fibroblast (WI-38) cells
Formula: C22H19N3O6
consists of polyallylamine that is crosslinked with epichlorohydrin
CAS Number: 1957236-22-4
8(9):10355-64
(S)-WAY 100135 dihydrochloride thacholine chloride 72 hours) shows no detectable(S) WAY 100135 dihydrochloride is a potent and selective antagonist of 5 HT1A receptor with IC50 value of 15 nM. The 5 HT1A receptor is a G protein coupled receptor for endogenous neurotransmitter serotonin (5 HT) and mediates inhibitory neurotransmission. (S) WAY 100135 dihydrochloride is a potent and selective somatodendritic and postsynaptic 5 HT1A receptors antagonist. (+ ) WAY100135 inhibited 5 HT1A receptor in the rat hippocampal with IC50 value
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