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YNT-185 - CAS# 1804978-81-1 vir (MK-0518) AZD-9291 shows similar potency to

SKU: 56815607841

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Description

AZD-9291 shows similar potency to early generation tyrosine kinase inhibitor (TKIs) in inhibiting EGFR phosphorylation in EGFR cells harboring sensitising EGFR mutants including PC-9 (ex19del)

Formula: C25H51N3O12

5-dihydroxyoxan-2-yl (4aR

Molecular Weight: 932

Ketanserin significantly prolongs action potential duration (APD) at 50% repolarization by 218% and APD at 90% repolarization by 256% with no significant effect on other action potential parameters in rat ventricular myocytes

YNT-185 - CAS# 1804978-81-1 vir (MK-0518) AZD-9291 shows similar potency toYNT 185 is a nonpeptide, selective orexin type 2 receptor (OX2R) agonist, with EC50s of 0. 028 and 2. 75 M for OX2R and OX1R, respectively. YNT 185 ameliorates narcolepsy cataplexy symptoms in mouse models. Product information CAS Number: 1804978 81 1 Molecular Weight: 615. 74 Formula: C33H37N5O5S Chemical Name: 3' ({3 [(2 {[2 (dimethylamino)phenyl]formamido}ethyl)amino]phenyl}sulfamoyl) 4' methoxy N, N dimethyl [1, 1' biphenyl] 3 carboxamide Smiles:

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