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InChiKey: IXEPQJQQSLMESJ-UHFFFAOYSA-N
STAT5-IN-2 is a STAT5 inhibitor
UBP-282 inhibits the fast component of the dorsal root-evoked ventral root potential (fDR-VRP) with an IC50 value of 10
CGS 21680 potently stimulates the formation of cAMP with an EC50 of 110 nM but is ineffective at inhibiting electrically stimulated dopamine release
Exposure of cells to Genz-123346 and to other GCS inhibitors at non-toxic concentrations can enhance the killing of tumor cells by cytotoxic anti-cancer agents
α-Guanidinoglutaric Acid rulline InChiKey: IXEPQJQQSLMESJ-UHFFFAOYSA-NGuanidinoglutaric Acid is a novel nitric oxide synthase inhibitor with Ki value of 2. 69 M . In the brain, nitric oxide (NO), which is synthesized from L arginine (Arg) by NO synthase (NOS), acts as both an intra and an intercellular second messenger, and it may suppress convulsions . Guanidinoglutaric Acid (GGA) is a novel nitric oxide synthase inhibitor. GGA was increased in the cobalt induced epileptic focus tissue in the cerebral cortex of cats .
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