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PDE2/PDE10-IN-1 e Isomer II PubMed PMID: 23151808

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Description

PubMed PMID: 23151808

and has a favorable pharmacokinetic and toxicity profile

5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)prop-2-enoate

30(2):497-509

InChi: InChI=1S/C41H62N12O11/c1-5-22(4)33(38(61)50-29(17-24-19-45-20-47-24)39(62)53-15-7-9-30(53)40(63)64)52-36(59)28(16-23-10-12-25(54)13-11-23)49-37(60)32(21(2)3)51-35(58)27(8-6-14-46-41(43)44)48-34(57)26(42)18-31(55)56/h10-13

PDE2/PDE10-IN-1 e Isomer II PubMed PMID: 23151808PDE2 PDE10 IN 1 is a phosphodiesterase 2 (PDE2) and PDE10 inhibitor with IC50s of 29 and 480 nM, respectively. Product information CAS Number: 1426833 08 0 Molecular Weight: 295. 73 Formula: C15H10ClN5 Chemical Name: 3 (2 chlorophenyl) 7 methyl 2,4,5,8,12 pentaazatricyclo[7. 4. 0. 0,]trideca 1(13),3,5,7,9,11 hexaene Smiles: CC1=NC2=CC=NC=C2N2C1=NN=C2C1=CC=CC=C1Cl InChiKey: SNQXTEAQGLZIDL UHFFFAOYSA N InChi: InChI=1S C15H10ClN5 c1 9 14 19 20 15(10 4 2

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