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Azeliragon dihydrochloride
5-bis(trifluoromethyl)phenyl]-2-(H)methyl-N-methyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl](H)propanamide
The maximal potentiation at this concentration of glutamate is approximately 3
Smiles: CC(C)C[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)N[C@@H](CCC(=O)OC)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC(=O)OC)C(=O)CF
thereby ameliorating muscle wasting in the hypermetabolic state of cancer cachexia
CP-547632 3654 Azeliragon dihydrochlorideCP 547632 is an orally active, ATP competitive and potent VEGFR 2 and FGF kinases inhibitor with IC50s of 11 nM and 9 nM, respectively. CP 547632 is selective for VEGFR2 and bFGF over EGFR, PDGFR, and related tyrosine kinases (TKs). CP 547632 has antitumor efficacy. Product information CAS Number: 252003 65 9 Molecular Weight: 532. 40 Formula: C20H24BrF2N5O3S Chemical Name: 3 [(4 bromo 2,6 difluorophenyl)methoxy] 5 ({[4 (pyrrolidin 1
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