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2011 Feb
Discovery of a First-in-Class Mitogen-Activated Protein Kinase Kinase 1/2 Degrader
As serine/threonine protein kinases which are involved in a number of biological processes
AM-2394 activates glucokinase (GK) with an EC50 of 60 nM
InChi: InChI=1S/C71H110N24O18S/c1-35(2)24-46(93-68(112)51(14-11-22-80-70(77)78)95-57(102)19-21-71(95
ONO-9780307 - CAS# 856691-44-6 42834 2011 FebONO 9780307 is a specific synthetic LPA1 (lysophosphatidic acid receptor 1) antagonist with an IC50 value of 2. 7 nM. Product information CAS Number: 856691 44 6 Molecular Weight: 521. 60 Formula: C30H35NO7 Chemical Name: 2 {1 [(2S, 3S) 2 [(2, 3 dihydro 1H inden 2 yl)methyl] 3 (3, 5 dimethoxy 4 methylphenyl) 3 hydroxypropyl] 4 (methoxycarbonyl) 1H pyrrol 3 yl}acetic acid Smiles:
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