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likely occupying a similar site within the ligand-binding domain
with an IC50 of 3
ICRT-14 can interfere with TCF binding to DNA in addition to its ability to influence TCF-β-cat interaction
Dovitinib (10 mg/kg
Molecular Weight: 417
Rolapitant - CAS# 552292-08-7 Catalog No.:M6632-10 likely occupying a similar siteRolapitant, CAS No. 552292 08 7, also known as SCH 619734, is an orally bioavailable, centrally acting, selective, neurokinin 1 receptor (NK1 receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1 receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP). This may prevent both SP induced emesis and
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