AG-490 CI-006 (-)-Narwedine reduces the action of

(-)-Narwedine reduces the action of AChE and therefore tends to increase the concentration of acetylcholine in the brain

7(8):e44021

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and 890 nM

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AG-490 CI-006 (-)-Narwedine reduces the action ofTyrphostin AG490 is a JAK 2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT 3], and subsequently reduce invasion and adhesion potential of malignant cells. The hematopoietic cancer c Kit+, Jak 2+ and non hematopoietic tumors c Kit+, HER 2+, JAK 2+ can be inhibited by the chemosensitizing agent AG490 causing programmed cell death. Product information CAS Number: 133550 30 8