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KT5823 - CAS# 126643-37-6 Catalog No.:M11738-10 1883545-53-6 (2HCl)

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Description

1883545-53-6 (2HCl)

3-dihydrobenzofuran-3-yl)acetic acid

PDGFR and MAPK signaling pathways as compared to the parent compound

4-dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol

99533-80-9

KT5823 - CAS# 126643-37-6 Catalog No.:M11738-10 1883545-53-6 (2HCl)KT5823, a selective the cGMP dependent protein kinase (PKG) inhibitor with an Ki value of 0. 23 M, it also inhibits PKA and PKC with Ki values of 10 M and 4 M, respectively. KT5823 is a staurosporine related protein kinase inhibitor, increases thyroid stimulating hormone induced (Na+ I symporter) NIS expression, and iodide uptake in thyroid cells. KT5823 arrests cells after the G0 G1 boundary and causes increases in the levels of apoptotic DNA

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