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FG-2216 showed the ability to stabilize HIF-α
Vericiguat (BAY1021189
Thomas-Tran
RA190 administration profoundly reduced growth of MM and ovarian cancer xenografts
J Biomol Struct Dyn
GMB 475 Catalog No.:M7570-10 FG-2216 showed the ability toBCR ABL1 kinase PROTAC Degrader. Induces degradation of BCR ABL1 and cABL1, inhibits downstream STAT5 signaling and suppresses cell proliferation in chronic myeloid leukemia cells lines. Product information CAS Number: 2490599 18 1 Molecular Weight: 861. 93 Formula: C43H46F3N7O7S Synonym: GMB475 GMB 475 Chemical Name: (2S) 1 ((R) 3,3 dimethyl 2 (2 (2 (4 (6 ((4 (trifluoromethoxy)phenyl)amino)pyrimidin 4 yl)phenoxy)ethoxy)acetamido)butanoyl) 4 hydroxy N
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