TAK-700 R-form Catalog No.:M22571-C InChi: InChI=1S/C28H33NO3/c1-21(2)26(30)31-20-12-6-5-11-19-29-24-15-9-8-14-23(24)27(3

InChi: InChI=1S/C28H33NO3/c1-21(2)26(30)31-20-12-6-5-11-19-29-24-15-9-8-14-23(24)27(3

InChiKey: TVJRDCQUZMGBAB-UHFFFAOYSA-N

Smiles: C#CCOCCOCCOCCOCCOCCOCCOCCO

CAS Number: 81836-41-1

JPH203 Dihydrochloride is a tyrosine analog

TAK-700 R-form Catalog No.:M22571-C InChi: InChI=1S/C28H33NO3/c1-21(2)26(30)31-20-12-6-5-11-19-29-24-15-9-8-14-23(24)27(3TAK 700 R form is a highly selective inhibitor of 17, 20 lyase with IC50 value of 38nM . TAK 700 is a potent and selective inhibitor of the 17, 20 lyase activity of CYP17A1 which is responsible for androgen biosynthesis. Thus, TAK 700 is selected as a candidate for treatment of prostate cancer through reducing the adrenal androgen production. As an inhibitor of CYP17A1, the selectivity of TAK 700 is important to avoid causing the drugdrug interactions