Duocarmycin A F265 ) dose dependently lowers blood

) dose dependently lowers blood pressure in hypertensive SHRs[1]

3-benzodioxole-5-carboxylate

01) and further lowered to 68% of control at 10 µM

compound 2c) is a potent

6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-2

Duocarmycin A F265 ) dose dependently lowers bloodDuocarmycin A, which is one of well known antitumor antibiotics, is a DNA alkylator and efficiently alkylates adenine N3 at the 3 end of AT rich sequences in the DNA. Duocarmycin A, as a chemotherapeutic agent, results HLC 2 cells typically apoptotic changes, including chromatin condensation, sub G1 accumulation in DNA histogram pattern, and decrease in procaspase 3 and 9 levels. Product information CAS Number: 118292 34 5 Molecular Weight: 507. 49