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AZD3839 free base - CAS# 1227163-84-9 2302 Formula: C25H26N7O8P

SKU: 50620794250

4.8
USD100.00 USD127.00

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Description

Formula: C25H26N7O8P

41(5):1192-9

3)23-21-25/h25H

InChiKey: AJULRUMEMZKBQI-UHFFFAOYSA-N

Smiles: C[C@@]12CC[C@]3(CCC(C)(C)C[C@H]3C1=CC[C@H]1[C@@]2(C)CC[C@@H]2[C@]1(C)CC[C@H](O)C2(C)C)C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

AZD3839 free base - CAS# 1227163-84-9 2302 Formula: C25H26N7O8PAZD3839 free base is a potent and selective orally active, brain permeable BACE1 inhibitor (Ki=26 nM). AZD3839 free base shows 14 and >1000 fold selectivity against BACE2 and cathepsin D, respectively. AZD3839 free base exhibits dose and time dependent lowering of plasma, brain, and cerebrospinal fluid A levels in mouse, guinea pig, and non human primate. AZD3839 free base can be used for the research of Alzheimer's disease. Product information CAS

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