7-Hydroxycoumarinyl arachidonate Catalog No.:M19002-C PIK-90 completely inhibits the fMLP-stimulated

PIK-90 completely inhibits the fMLP-stimulated phosphorylation of Akt and impairs polarity and chemotaxis in dHL60 cells

This leads to the cell's death via loss of intracellular elements

N3-TEG-COOH

50)51)11-19-9-21(55(43

4-oxadiazol-3-yl)benzamide

7-Hydroxycoumarinyl arachidonate Catalog No.:M19002-C PIK-90 completely inhibits the fMLP-stimulated7 Hydroxycoumarinyl arachidonate (7 HCA) is a fluorogenic substrate of cytosolic phospholipase A2 (PLA2). 7 Hydroxycoumarinyl arachidonate is also a fluorogenic substrate for monoacylglycerol lipase (MAGL). MAGL protein catalyzes the hydrolysis of 7 Hydroxycoumarinyl arachidonat to generate Arachidonic acid (AA) and the highly fluorescent 7 hydroxyl coumarin (7 HC; HY N0573). Release of 7 HC can be measured using a fluorometer. Product information CAS