L-873724 ressin acetate 5-a]pyrimidin-3-yl]ethynyl}pyridin-2-amine

5-a]pyrimidin-3-yl]ethynyl}pyridin-2-amine

9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}pyrimidin-4-yl)amino]-N-methylbenzamide

for 22 days) has antiarthritic activity

4-Di-O-caffeoylquinic acid

Oral administration of ZSTK474 inhibits the growth of subcutaneously implanted mouse B16F10 melanoma tumors in a dose-dependent manner

L-873724 ressin acetate 5-a]pyrimidin-3-yl]ethynyl}pyridin-2-amineL 873724 is a potent, orally bioavailable, selective and reversible non basic cathepsin K inhibitor, with IC50s of 0. 2, 178, 264, and 5239 nM for cathepsin K, cathepsin S, cathepsin L, cathepsin B, respectively. L 873724 also exhibits an IC50 of 0. 5 nM for rabbit cathepsin K. L 873724 inhibits bone resorption. Product information CAS Number: 603139 12 4 Molecular Weight: 481. 53 Formula: C23H26F3N3O3S Chemical Name: (2S) N (cyanomethyl) 4 methyl 2