SIRT1-IN-1 ydrate) 14R)-2-(((R)-1-(((S)-1-(((S)-1-((S)-2-(((R)-1-amino-1-oxopropan-2-yl)carbamoyl)pyrrolidin-1-yl)-6-(isopropylamino)-1-oxohexan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-1-oxo-3-(4-ureidophenyl)propan-2-yl)carbamoyl)-11-(4-chlorobenzyl)-5-(hydroxymethyl)-14-(naphthalen-2-ylmethyl)-4

14R)-2-(((R)-1-(((S)-1-(((S)-1-((S)-2-(((R)-1-amino-1-oxopropan-2-yl)carbamoyl)pyrrolidin-1-yl)-6-(isopropylamino)-1-oxohexan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-1-oxo-3-(4-ureidophenyl)propan-2-yl)carbamoyl)-11-(4-chlorobenzyl)-5-(hydroxymethyl)-14-(naphthalen-2-ylmethyl)-4

InChiKey: FNANNZAGLCKFOL-ZKTNFTSUSA-N

Epub 2017 Feb 6

Sirt2-PROTAC-1 is a SirReal based PROTAC

InChiKey: NXCPMSUBVRGTSE-UHFFFAOYSA-N

SIRT1-IN-1 ydrate) 14R)-2-(((R)-1-(((S)-1-(((S)-1-((S)-2-(((R)-1-amino-1-oxopropan-2-yl)carbamoyl)pyrrolidin-1-yl)-6-(isopropylamino)-1-oxohexan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-1-oxo-3-(4-ureidophenyl)propan-2-yl)carbamoyl)-11-(4-chlorobenzyl)-5-(hydroxymethyl)-14-(naphthalen-2-ylmethyl)-4SIRT1 IN 1 is a selective SIRT1 inhibitor with an IC50 of 0. 205 M. SIRT1 IN 1 inhibits SIRT2 with an IC50 of 11. 5 M. SIRT1 IN 1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity. Product information CAS Number: 352554 02 0 Molecular Weight: 228. 29 Formula: C14H16N2O Chemical Name: 6 methyl 2,3,4,9 tetrahydro 1H carbazole 1 carboxamide Smiles: CC1=CC=C2NC3C(CCCC=3C2=C1)C(N)=O InChiKey: KQWPYXBWZWLRMZ UHFFFAOYSA N InChi: