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108(2):205-8
InChi: InChI=1S/C31H38N2O5/c1-20(2)32-31(34)30(22-10-8-7-9-11-22)33-15-14-23-18-28(37-5)29(38-6)19-24(23)25(33)16-21-12-13-26(35-3)27(17-21)36-4/h7-13
muris-infected mice
but has much less effect on Src (IC50 values 0
PF-622 is a potent
Lopinavir-d8 0658 108(2):205-8Lopinavir d8 (ABT 378 d8) is the deuterium labeled Lopinavir. Lopinavir (ABT 378) is a highly potent, selective peptidomimetic inhibitor of the HIV 1 protease, with Kis of 1. 3 to 3. 6 pM for wild type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV 1 thereby blocking its infectivity. Lopinavir is also a SARS CoV 3CLpro inhibitor with an IC50 of 14. 2 M. Product information CAS Number: 1224729 35 4 Molecular Weight: 636. 85
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