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Coumarin is the primary bioactive ingredient in Radix Glehniae
PubMed PMID: 25381820
AP521 is an agonist of human 5-HT1A receptor with an IC50 of 94 nM
αIIBβ3 integrins
24)/b14-9-
Eeyarestatin I ic acid A anhydride-d3 Coumarin is the primary bioactiveEeyarestatin I, a potent endoplasmic reticulum associated protein degradation (ERAD) inhibitor, is a potent protein translocation inhibitor. Eeyarestatin I targets the p97 associated deubiquitinating process (PAD) and inhibits atx3 dependent deubiquitination. Eeyarestatin I induces cell death via the proapoptotic protein NOXA and has anticancer effects. Product information CAS Number: 412960 54 4 Molecular Weight: 630. 44 Formula: C27H25Cl2N7O7