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AZD-5438 702 also known as gold thioglucose

SKU: 45702387538

4.5
USD85.00 USD120.00

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Description

also known as gold thioglucose and Solganal

It acts as an antioxidant according to in vitro studies

InChiKey: NYHXPFHFIMRKDS-UHFFFAOYSA-N

also known as SM04690

1371/journal

AZD-5438 702 also known as gold thioglucoseAZD5438 is a potent inhibitor of cyclin dependent kinase (cdk) 1, 2, and 9 (IC(50), 16, 6, and 20 nmol L, respectively). In vitro, AZD5438 showed significant antiproliferative activity in human tumor cell lines (IC(50) range, 0. 2 1. 7 micromol L), causing inhibition of the phosphorylation of cdk substrates pRb, nucleolin, protein phosphatase 1a, and RNA polymerase II COOH terminal domain and blocking cell cycling at G(2) M, S, and G(1) phases.

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