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4'-Ethynyl-2'-deoxyadenosine olidin 10(12):2267-75

SKU: 45209553467

4.3
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Description

10(12):2267-75

2013 Dec 24

(Z)-N-[(2R)-2-hydroxy-3-(piperidin-1-yl)propoxy]-1-oxo-1λ⁵-pyridine-3-carbonimidoyl chloride

Papaevgeniou N

Smiles: CC1C=C(C=C(C)C=1OCCCC1=CC(C)=NO1)C1=NOC(=N1)C(F)(F)F

4'-Ethynyl-2'-deoxyadenosine olidin 10(12):2267-754' Ethynyl 2' deoxyadenosine (4' E dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug resistant HIV variants, with an EC50 of 98 nM in MT 4 cells for anti HIV 1 activity. Product information CAS Number: 306305 07 7 Molecular Weight: 275. 26 Formula: C12H13N5O3 Chemical Name: (2R) 5 (6 amino 9H purin 9 yl) 2 ethynyl 2 (hydroxymethyl)oxolan 3 ol Smiles: C#C[C@]1(CO)OC(CC1O)N1C=NC2=C(N)N=CN=C12

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