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binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site
the activity of LX7101 is primarily due to inhibition of LIMK2
InChi: InChI=1S/C22H26O8/c1-12(7-8-23)21(26)29-19-10-16(11-24)5-6-17(28-15(4)25)13(2)9-18-20(19)14(3)22(27)30-18/h5
InChiKey: PCQWDGGWAHUXTQ-OUSXHNLLSA-N
but not APC-Sam68 or APC-striatin interactions
Cinchonidine 2142 binds simultaneously with ATP inCinchonidine ( Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with Kis of 330, 4. 2, 36, 196, 15 M for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively. Antimalarial activities. Product information CAS Number: 485 71 2 Molecular Weight: 294. 39 Formula: C19H22N2O Chemical Name:
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