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0 nM in IMR-32 cells
fortuitumi)
4-diphenyl-2
45)22-4-5-22)36-16-23(24)29-25(43)12-21(41-10-8-40(3)9-11-41)13-26(29)46-18-31(32
Formula: C57H65F5N10O8
Talabostat Catalog No.:M19987-C 0 nM in IMR-32 cellsTalabostat (Val boroPro; PT100) is an orally active and nonselective dipeptidyl peptidase IV (DPP IV) inhibitor (IC50 < 4 nM; Ki = 0. 18 nM) and the first clinical inhibitor of fibroblast activation protein (FAP) (IC50 = 560 nM), inhibits DPP8 9 (IC50 = 4 11 nM; Ki = 1. 5 0. 76 nM), quiescent cell proline dipeptidase (QPP) (IC50 = 310 nM), DPP2, and some other DASH family enzymes. Antineoplastic and hematopoiesis stimulating activities. Product
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