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Interplaybetween Polo kinase
2016 Aug 5
0037 μg/mL
3 μM and has anti-necroptosis activity
InChiKey: LEXMMFPAPDGYGZ-UHFFFAOYSA-N
PRI-724 - CAS# 1422253-38-0 60101 Interplaybetween Polo kinasePRI 724, CAS No. 1422253 38 0, also known as C 82 prodrug ICG 001 analog, is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity. Wnt signaling pathway inhibitor PRI 724 specifically inhibits the recruiting of beta catenin with its coactivator CBP (the binding protein of the cAMP response element binding protein CREB); together with other transcription factors beta catenin CBP
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