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Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression
it possesses more than 60-fold selectivity for inhibition of TASK1 over a closely-related
also known as ARRY-520
Formula: C7H17ClN2O2
InChiKey: FICWTZOQUXUYOK-AHKKVLALSA-N
XCT790 - CAS# 725247-18-7 Size:Solid 10 mg Discovery of a Small-Molecule DegraderXCT790 is a selective ERR antagonist inverse agonist (IC50 = ~400 nM). XCT790 displays no antagonist activity at ERR or ER at concentrations below 10 M. It interferes with PPAR coactivator 1 (PGC 1) ERR dependent signaling. Product information CAS Number: 725247 18 7 Molecular Weight: 596. 42 Formula: C23H13F9N4O3S Synonym: XCT 790 XCT 790 Chemical Name: (2E) 3 (4 {[2,4 bis(trifluoromethyl)phenyl]methoxy} 3 methoxyphenyl) 2 cyano N [5