PROTAC BRD4 Degrader-5 Catalog No.:M8001-10 InChi: InChI=1S/C31H29N3O5/c1-20(35)32-24-12-14-25(15-13-24)39-19-23-17-22(11-16-28(23)38-2)30-33-26-9-6-10-27(36)29(26)31(37)34(30)18-21-7-4-3-5-8-21/h3-17

InChi: InChI=1S/C31H29N3O5/c1-20(35)32-24-12-14-25(15-13-24)39-19-23-17-22(11-16-28(23)38-2)30-33-26-9-6-10-27(36)29(26)31(37)34(30)18-21-7-4-3-5-8-21/h3-17

InChi: InChI=1S/C25H19NO3S/c27-21-15-23(26-11-13-28-14-12-26)29-24-17(6-3-9-20(21)24)19-8-4-7-18-16-5-1-2-10-22(16)30-25(18)19/h1-10

2 μM and 20 μM

This is consistent across both models

polycythemia vera

PROTAC BRD4 Degrader-5 Catalog No.:M8001-10 InChi: InChI=1S/C31H29N3O5/c1-20(35)32-24-12-14-25(15-13-24)39-19-23-17-22(11-16-28(23)38-2)30-33-26-9-6-10-27(36)29(26)31(37)34(30)18-21-7-4-3-5-8-21/h3-17PROTAC BRD4 Degrader 5 is a PROTAC based BRD4 degrader. PROTAC BRD4 Degrader 5 can potent degrade BRD4 in HER2 positive and negative breast cancer cell lines. Product information CAS Number: 2409538 70 9 Molecular Weight: 1016. 67 Formula: C50H62ClN9O8S2 Chemical Name: (2S, 4R) 1 [(2S) 2 (2 {2 [2 (2 {2 [(9S) 7 (4 chlorophenyl) 4, 5, 13 trimethyl 3 thia 1, 8, 11, 12 tetraazatricyclo[8. 3. 0. 0, ]trideca 2(6), 4, 7, 10, 12 pentaen 9