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Abstract 1045
2 substrates of this enzyme
Macitentan (trade name Opsumit) is an endothelin receptor antagonist (ERA) approved for the treatment of pulmonary arterial hypertension (PAH)
Aurintricarboxylic acid weakly inhibits P2X2/3Rs
Chemical Name: 2-[2-(2-bromoethoxy)ethoxy]-N-ethylacetamide
Amikacin hydrate ingolimod hydrochloride Abstract 1045Amikacin hydrate (BAY 41 6551 hydrate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin hydrate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin hydrate is very active against most Gram negative bacteria including gentamicin and tobramycin resistant strains. Amikacin hydrate also inhibits the infections caused by susceptible Nocardia and