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Ceralasertib (AZD6738) inhibits human breast cancer cell lines with IC50 values less than 1 μM using MTT assay
70 nM and 200 nM
CAS Number: 100643-71-8
Solubility: H2O : 125 mg/mL (1145
α2-adrenergic receptors include three subtypes: α2A
U-44069 Size:Contact [email protected] for quotation Ceralasertib (AZD6738) inhibits human breastEC50: 3 M and 54 nM for platelet aggregation and phosphatidate formation in human platelets, respectively U 44069 is a TP receptor agonist. Increased production of vasoconstrictive prostanoids, such as thromboxane A2, contributes to endothelial dysfunction and increased hepatic vascular tone in cirrhosis. Thromboxane A2 induces vasoconstriction via activation of the thromboxane A2 prostaglandin endoperoxide (TP) receptor. In vitro: In a previous
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