BAY K 8644 ittin 56-39)40(48)41(49)45-16-12-11-13-32(45)42(50)55-38(28(6)33(46)23-34(30)47)26(4)20-29-14-15-31(44)35(22-29)52-7/h18

56-39)40(48)41(49)45-16-12-11-13-32(45)42(50)55-38(28(6)33(46)23-34(30)47)26(4)20-29-14-15-31(44)35(22-29)52-7/h18

5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide

The anti-tumor effects of PLX-4720 correlate with the blockade of MAPK pathway in those cells harboring the V600E mutation

Italiano K

PubMed Central PMCID: PMC4222641

BAY K 8644 ittin 56-39)40(48)41(49)45-16-12-11-13-32(45)42(50)55-38(28(6)33(46)23-34(30)47)26(4)20-29-14-15-31(44)35(22-29)52-7/h18Bay K 8644 is a potent selective activator of L type Ca2 channel with IC50 of 173 nM Product information CAS Number: 71145 03 4 Molecular Weight: 356. 30 Formula: C16H15F3N2O4 Chemical Name: methyl 2,6 dimethyl 5 nitro 4 [2 (trifluoromethyl)phenyl] 1,4 dihydropyridine 3 carboxylate Smiles: COC(=O)C1C(C(=C(C)NC=1C)[N+]([O ])=O)C1=CC=CC=C1C(F)(F)F InChiKey: ZFLWDHHVRRZMEI UHFFFAOYSA N InChi: InChI=1S C16H15F3N2O4 c1 8 12(15(22)25 3)13(14(21(23)24)9(2)20