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a novel plasminogen activator inhibitor-1 inhibitor
]hexadec-1(16)-en-8-yl acetate
InChi: InChI=1S/C23H15ClF2N2O2/c24-16-8-6-15(7-9-16)23-18-4-2-1-3-17(18)22(30)28(23)12-11-27(23)21(29)14-5-10-19(25)20(26)13-14/h1-10
InChiKey: BBTFKAOFCSOZMB-UHFFFAOYSA-N
Epub 2015 Jun 1
AR-M 1896 Size:Contact [email protected] for quotation a novel plasminogen activator inhibitor-1Binding IC50: 1. 76 nM for rGalR2; 879 nM for hGalR1 Galanin is a 29 aa neuropeptide with a complex role in pain processing. Galanin receptor subtypes are present in dorsal root ganglia and spinal cord with a differential distribution. Three galanin receptors, GalR1, GalR2 and GalR3, have been identified and cloned. AR M1896 is a specific galanin R2 (GalR2) agonist. In vitro: Additional removal of the glycine residue in position 1 resulted in AR M1896
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