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Tyrphostin AG490 is a JAK-2 specific inhibitor
Displays no antitumor activity in vitro or in vivo
As with recombinant cell systems
484(3):486-492
59(7):4020-5
Matrine lenib (GS-9876) Tyrphostin AG490 is a JAK-2Matrine (Matridin 15 one) is an alkaloid found in plants from the Sophora genus. It has a variety of pharmacological effects, including anti cancer effects, and action as a kappa opioid receptor and u receptor agonist. Product information CAS Number: 519 02 8 Molecular Weight: 248. 36 Formula: C15H24N2O Synonym: Matridin 15 one NSC 146051 NSC146051 NSC 146051 Chemical Name: (1R, 2R, 9S, 17S) 7, 13 diazatetracyclo[7. 7. 1. 0, . 0, ]heptadecan 6 one