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58(17):3883-90
3-thiazol-5-yl)phenyl]-8-ethyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-7H
suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a
ATB-346 may therefore be an attractive agent for chemoprevention of colon cancer
Morizumi S
Gefitinib impurity 2 Catalog No.:M31681-C 58(17):3883-90Gefitinib impurity 2 is the impurity of Gefitinib. Gefitinib (ZD1839; HY 50895) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity. Product information CAS Number: 246512 44 7 Molecular
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