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Transfection of Poly (I:C) into NIT-1 cells has been used as a model of intracellular dsRNA-induced β cell apoptosis
Anti-pcsk9 compounds and methods for the treatment and/or prevention of cardiovascular diseases
Solubility: DMSO : 125 mg/mL (352
CAS Number: 315698-07-8
Treatment of P
CpdA Size:Contact [email protected] for quotation Transfection of Poly (I:C) intoCpdA is a non steroidal selective glucocorticoid receptor modulator. It is an aziridine precursor that can infiltrate cells and is translocated to the nucleus. It inhibits glucocorticoid receptor dimerization, which prevents transcription of gene targets such as NF B and subsequent cytokines through transrepression. Studies have shown contradictory results for binding affinity of CpdA compared with dexamethasone that were either higher (4 fold, IC50 =
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