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N-Oxalylglycine taminyl Cyclase Inhibitor 2 InChi: InChI=1S/C17H20N4/c1-20-9-14-11-21(12-15(14)10-20)17-8-7-16(18-19-17)13-5-3-2-4-6-13/h2-8

SKU: 41079769007

4.6
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Description

InChi: InChI=1S/C17H20N4/c1-20-9-14-11-21(12-15(14)10-20)17-8-7-16(18-19-17)13-5-3-2-4-6-13/h2-8

1 nM in SK-OV-3 cells that calculated from the free fraction in the cell assay

InChiKey: JDBJJCWRXSVHOQ-IZHPGBHVSA-N

32)33)16-41-11-9-24(17-41)40(2)3/h4-8

Smiles: OCC(S)CS

N-Oxalylglycine taminyl Cyclase Inhibitor 2 InChi: InChI=1S/C17H20N4/c1-20-9-14-11-21(12-15(14)10-20)17-8-7-16(18-19-17)13-5-3-2-4-6-13/h2-8The jumonji domain containing protein 2 (JMJD2) subfamily of histone demethylases have been shown to catalyze demethylation of the methylated forms of histone 3 lysine 9 (H3K9) and H3K36 in vitro and in cells. Because histone demethylases are implicated in certain diseases, including cancer, selective inhibitors are candidate anticancer agents as well as potential tools for elucidating the biological functions of JMJDs. 2 N Oxalylglycine, the amide

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