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Pulsatilla saponin D (SB365)
Smiles: CC(C)C(=O)O[C@H]1[C@H](O)[C@H](O)[C@H](O[C@@H]2[C@@H](CC)C=C(C)[C@@H](O)CC=CC=C(CO[C@@H]3O[C@H](C)[C@@H](OC(=O)C4C(O)=C(Cl)C(O)=C(Cl)C=4CC)[C@H](O)[C@@H]3OC)C(=O)O[C@@H](CC=C(C)C=C2C)[C@@H](C)O)OC1(C)C |c:17
InChi: InChI=1S/C26H32O11/c1-10(2)6-15(28)37-18-20-25-9-35-26(20
InChi: InChI=1S/C13H8N4O/c14-6-10(13(17)11(7-15)8-16)5-9-1-3-12(18)4-2-9/h1-5
selective JAK1/2 inhibitor to enter the clinic with IC50s of 3
Hu7691 free base zilin Pulsatilla saponin D (SB365)Hu7691 free base is an orally active, selective Akt inhibitor with IC50s of 4. 0 nM, 97. 5 nM, 28 nM for Akt1, Akt2 and Akt3, respectively. Hu7691 free base inhibits tumor growth and enables decrease of cutaneous toxicity in mice. Product information CAS Number: 2241232 43 7 Molecular Weight: 414. 42 Formula: C22H21F3N4O Chemical Name: N ((3S, 4S) 4 (3, 4 difluorophenyl)piperidin 3 yl) 2 fluoro 4 (1 methyl 1H pyrazol 5 yl)benzamide Smiles: