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Oral gavage of AT13148 at well-tolerated doses significantly inhibits HGC27 xenograft tumor growth in nude mice
mTOR-IN-1 achieves tumor stasis at the highest 200 mg/kg/day dose examined
Formula: C18H23NO4
Chemical Name: tert-butyl N-(6-bromohexyl)carbamate
Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
C-7280948 C6-NH2 dihydrochloride Oral gavage of AT13148 atC 7280948 is a selective and potent protein methyltransferase1 (PRMT1) inhibitor with an IC50 value of 12. 75 M. Product information CAS Number: 587850 67 7 Molecular Weight: 276. 35 Formula: C14H16N2O2S Chemical Name: 4 amino N (2 phenylethyl)benzene 1 sulfonamide Smiles: NC1C=CC(=CC=1)S(=O)(=O)NCCC1C=CC=CC=1 InChiKey: BYWZPUPRVIECEC UHFFFAOYSA N InChi: InChI=1S C14H16N2O2S c15 13 6 8 14(9 7 13)19(17,18)16 11 10 12 4 2 1 3 5 12 h1 9,16H,10 11,15H2
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