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Pustovit K
2013 Dec 9
AK-7 is a good chemical probe to study SIRT2’s roles in metabolic diseases
Acute CTEP treatment corrects elevated hippocampal long-term depression
Treatment of two mouse models of obesity/diabetes with WWL113 ameliorates multiple features of metabolic syndrome
PLX-4720 - CAS# 918505-84-7 60209 Pustovit KPLX 4720, CAS No. 918505 84 7, is a 7 azaindole derivative that inhibits B Raf(V600E) with an IC(50) of 13 nM, defines a class of kinase inhibitor with marked selectivity in both biochemical and cellular assays. PLX 4720 preferentially inhibits the active B Raf(V600E) kinase compared with a broad spectrum of other kinases, and potent cytotoxic effects are also exclusive to cells bearing the V600E allele. Product information CAS Number: 918505 84 7
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