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High survivin expression in the primary tumor is almost invariably associated with poor patient prognosis in many cancer types
C527 treatments lead to an increase in ubiquitinated forms of FANCD2 and FANCI
Is a Therapeutic Candidate against Nasopharyngeal Carcinoma
ClH/c1-28-19(5-8-25-28)27-21-24-7-4-17(26-21)13-6-9-29(20(31)11-13)18(12-30)14-2-3-15(22)16(23)10-14
5-di-tert-butyl-4-hydroxyphenyl)methylidene]-2-ethyl-1λ⁶
MLT-747 Size:Contact [email protected] for quotation High survivin expression in theMLT 747 is a potent, selective, allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 14 nM. Product information CAS Number: 2097853 86 4 Molecular Weight: 478. 33 Formula: C20H21Cl2N7O3 Chemical Name: 1 [5 chloro 6 (pyrrolidine 1 carbonyl)pyridin 3 yl] 3 {2 chloro 7 [(1S) 1 methoxyethyl]pyrazolo[1,5 a]pyrimidin 6 yl}urea Smiles: CO[C@@H](C)C1=C(C=NC2=CC(Cl)=NN21)NC(=O)NC1=CN=C(C(Cl)=C1)C(=O)N1CCCC1 InChiKey:
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