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Nielsen AN
13)4-2-15(9(19)14-8(4)18)7-1-5(17)6(3-16)20-7/h2
InChiKey: SXILFEBNQCRWAL-VERCZQKXSA-N
and significantly reduces expression of VCAM-1
To test whether GSTO1-IN-1 had in vivo efficacy
Aficamten - CAS# 2364554-48-1 Catalog No.:M33502-2 Nielsen ANAficamten, CAS No. 2364554 48 1, also known as CK 3773274 and CK 274, is a Next Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy. Aficamten was designed to provide a predicted human half life (t1 2) appropriate for once a day (qd) dosing, to reach steady state within two weeks, to have no substantial cytochrome P450 induction or inhibition, and to have a wide therapeutic window in vivo with a clear pharmacokinetic
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