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Smiles: CN1CCN(CC2C=CC(=CC=2)C(=O)NC2=CC(NC3=NC(=CS3)C3=CN=CC=C3)=C(C)C=C2)CC1
Smiles: C[C@@H]1O[C@H](C[C@H](N)[C@@H]1O)O[C@H]1C[C@@](O)(CC2C1=C(O)C1C(=O)C3=C(C=CC=C3C(=O)C=1C=2O)OC)/C(/CO)=N/NC(=O)CCCCCN1C(=O)C=CC1=O
BRL-50481 has no significant effect by itself on κB-dependent transcription (5
Ro5-3335 (300 mg/kg/d
48 hours) may exerts its apoptotic effects by regulating the apoptotic proteins and the IAP family of proteins in A549 and H460 cells
W-54011 Catalog No.:M20237-C Smiles: CN1CCN(CC2C=CC(=CC=2)C(=O)NC2=CC(NC3=NC(=CS3)C3=CN=CC=C3)=C(C)C=C2)CC1W 54011 is a potent and orally active non peptide C5a receptor antagonist. W 54011 inhibits the binding of 125I labeled C5a to human neutrophils with a Ki value of 2. 2 nM. W 54011 also inhibits C5a induced intracellular Ca2+ mobilization, chemotaxis, and generation of ROS in human neutrophils with IC50s of 3. 1 nM, 2. 7 nM, and 1. 6 nM, respectively. Product information CAS Number: 405098 33 1 Molecular Weight: 493. 08 Formula: C30H37ClN2O2 Chemical