Pay in 4 interest-free payments of $269.98 Learn more
Ships within 48 hours · Estimated delivery Aug 14 - Aug 19
44)45)54-35(30)55-64(4
Eg5 InhibitorIII
Formula: C27H26ClN3O7S2
5 h and oral bioavailability of 100%
Smiles: CC1(C)C2[C@@H](OC(C)=O)C(=O)[C@@]3(C)[C@H]([C@H](OC(=O)C4C=CC=CC=4)[C@]1(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)/C(/C)=C/C)C1C=CC=CC=1)C=2C)[C@@]1(CO[C@@H]1C[C@@H]3O)OC(C)=O
YM 254890 Size:2mg solid 44)45)54-35(30)55-64(4G protein inhibitor. Potently inhibits Gq 11 heterotrimeric G protein signaling. Inhibits ATP UTP induced Ca2+ increase in HCAE cells expressing P2Y2 receptor (IC50 = 50 nM); carbachol induced production of IP1 in CHO cells expressing M1 receptor (IC50 = 95 nM); and ADP induced Ca2+ increase in platelets, in vitro (IC50 = 2 M). Also inhibits Gs induced cAMP elevation and G protein coupled MAPK ERK signaling. Product information CAS Number: 568580 02 9