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Huxtable RJ
BLZ945 showed effects of CSF1R inhibition on other tumor-infiltrating immune cells
2'-((9-isopropyl-6-((4-methoxybenzyl)amino)-9H-purin-2-yl)azanediyl)bis(ethan-1-ol)
InChiKey: ZEUXAIYYDDCIRX-UHFFFAOYSA-N
Chemical Name: 2-(4-(thiophene-2-carbonyl)phenyl)propanoic acid
AG 18 - CAS# 118409-57-7 diine hydrochloride Huxtable RJAG 18, also known as RG 50810; RG 50858; TX 825; Tyrphostin A23; Tyrphostin AG 18. AG 18 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 35 M in the human epidermoid carcinoma cell line A431. AG 18 inhibits internalization of the transferrin receptor by perturbing the interaction between tyrosine motifs and the medium chain subunit of the AP 2 adaptor complex. Product information CAS Number: 118409 57 7 Molecular
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