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a novel small-molecule mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo
K-Ras G12C-IN-2 is an irreversible covalent K-Ras G12C inhibitor
Formula: C29H27F5N2O6S
or serine/threonine kinases
α3β2 and α3β4 with IC50s of 7
O-1821 Catalog No.:M22754-C a novel small-molecule mer inhibitorO 1821 is an cannabidiol analog with similar structure to O 1918, a selective antagonist of abnormal cannabidiol. Abnormal cannabidiol, a synthetic regioisomer of cannabidiol, fails to elicit either central cannabinoid (CB1) or peripheral cannabinoid (CB2) receptors and is lack of psychotropic activity. It can induce endothelium dependent vasodilation through a CB1 CB2 nitric oxide independent mechanism. In vitro: O 1821 is a cannabidiol analog with
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