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PF-06826647 Size:100mg solid GBR-12935 is now widely used

SKU: 37489426905

4.8
USD140.00 USD182.00

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Description

GBR-12935 is now widely used in animal research into Parkinson's disease and the dopamine pathways in the brain

Ba/F3-TEL-TRKC (IC50 of 3

increases the proportions of S- and G2-phase BT-20 cells (5-20 μM)

PF-4136309

31(6):671-8

PF-06826647 Size:100mg solid GBR-12935 is now widely usedPF 06826647 (Tyk2 IN 8, compound 10) is a selective and orally administered inhibitor of tyrosine kinase 2 (TYK2) with IC50 of 17 nM for binding to TYK2 catalytically active JH1 domain. PF 06826647 (Tyk2 IN 8, compound 10) also inhibits JAK1 and JAK2 with IC50 of 383 nM and 74 nM, respectively. PF 06826647 (Tyk2 IN 8, compound 10) is used in the treatment of psoriasis (PSO). Product information CAS Number: 2127109 84 4 Molecular Weight: 383. 41

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