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Dorniak PL
Epub 2015 Dec 14
778270-11-4
Chemical Name: 4-(4-(1-methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-1H-imidazol-5-yl)benzonitrile
INCB024360
Manidipine dihydrochloride D7545 Dorniak PLManidipine dihydrochloride (CV 4093) is a dihydropyridine compound and a calcium channel blocker for Ca2+ current with IC50 of 2. 6 nM. IC50 value: 2. 6 nM Target: calcium channel Manidipine dihydrochloride is described to block T type Ca2+ channels specifically and is also described to have a high selectivity for the vasculature, presenting negligible cardiodepression as compared to other Ca2+ channel antagonists. Manidipine is also described to not
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