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highly potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP) with IC50 of 0
D-α-Hydroxyglutaric acid has also been proposed as an endogenous excitotoxic organic acid because it significantly decreased cell viability in neuronal cultures from chick embryo telencephalons and from neonatal rat hippocampus through stimulation of specific NMDA glutamate receptors
Kupffer cell TGF-β1 expression
Smiles: CN(CC1=CSC(=N1)C(C)C)C(=O)N[C@@H](CCN1CCOCC1)C(=O)N[C@@H](CC1C=CC=CC=1)CC[C@H](CC1C=CC=CC=1)NC(=O)OCC1=CN=CS1
Sunitinib (20-80 mg/kg/day) exhibits broad and potent dose-dependent anti-tumor activity against a variety of tumor xenograft models including HT-29
GDC-0927 Racemate isobutyryl-ciclesonide highly potent and selective bromodomainGDC 0927 Racemate (SRN 927 Racemate) is a degrader of estrogen receptor, potently inhibits ER activity, with an IC50 of 0. 2 nM, and is used in the research of ER related diseases. Product information CAS Number: 1443983 36 5 Molecular Weight: 461. 52 Formula: C28H28FNO4 Chemical Name: 2 (4 {2 [3 (fluoromethyl)azetidin 1 yl]ethoxy}phenyl) 3 (3 hydroxyphenyl) 4 methyl 2H chromen 6 ol Smiles: