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Differential biological effects of K252 kinase inhibitors are related to membrane solubility but not to permeability
ETP-46321 PK/PD studies showed time dependent downregulation of AKT(Ser473) phosphorylation
CAS Number: 138-59-0
Smiles: CC(C)C[C@H]([C@H](CCC)N(O)C=O)C(=O)N[C@@H](CCCCNC(=O)OCC1C=CC=CC=1)C(=O)NC1=NC=CS1
Solubility: DMSO : 320 mg/mL (763
3, 6, 9-Trioxaundecanedioic Acid Size:2mg solid Differential biological effects of K252369 Trioxaundecanedioic Acid is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 13887 98 4 Molecular Weight: 222. 19 Formula: C8H14O7 Chemical Name: 2 {2 [2 (carboxymethoxy)ethoxy]ethoxy}acetic acid Smiles: OC(=O)COCCOCCOCC(O)=O InChiKey: HJZZQNLKBWJYPD UHFFFAOYSA N InChi: InChI=1S C8H14O7 c9 7(10)5 14 3 1 13 2 4 15 6 8(11)12 h1 6H2,(H,9,10)(H,11,12) Technical Data Appearance: Solid Power Purity:
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